Having no accepted definition or criteria, clearly raises issues for both diagnosis and potential studies. ![]() A fundamental difficulty arises when there is no clear definition, epidemiology, pathophysiology, or diagnosis of MPS. Nonetheless, TrPs and myofascial pain are a hallmark. ![]() Some define it as a regional pain disorder, others define it on the basis of tenderness and associated painful spots. Myofascial pain syndrome (MPS) is an entity that still lacks a clear definition. Traditionally, “TrPs” are perceived as associated with MPS and differ from “tender points” mainly in that they radiate pain. TrPs are small and sensitive areas in a contracted muscle, that spontaneously or upon compression cause pain to a distant region, known as a referred pain zone. Commonly known as “muscle knots” myofascial pain usually arises in ’trigger points’ (TrPs) or ’tender spots’. Myofascial pain denotes a pain arising from muscle and fascia. Chronic pain is a major cause of morbidity and has a significant impact on quality of life.
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